__ Plaines Illinois Crossword Clue

We have the 3-letter answer for __ Plaines Illinois crossword clue, last seen in the USA Today Crossword December 25, 2025 puzzle. Let us help you solve the crossword clue that has you stumped so you can finish the puzzle.

__ Plaines Illinois Crossword Answer

→66.

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Helpful Hints

(noun)
1. a potent estrogen used in medicine and in feed for livestock and poultry
2. synthetic nonsteroid with the properties of estrogen; formerly used to treat menstrual problems but was found to be associated with vaginal cancers in the daughters of women so treated during pregnancy

Hint 2: Clue Definition

ILLINOIS (noun)
1. a midwestern state in north-central United States
2. a member of the Algonquian people formerly of Illinois and regions to the west

Hint 3: Anagram

Unscramble the letters below to solve for today's answer.
EDS

More USA Today Crossword (12/25/2025) Answers

Across

1. Big bodies of saltwater

5. Let in

10. Part of a Super Grover costume

14. Mineral no longer used in baby powder

15. Dirty gunk

16. App developer's customer

17. At Last singer James

18. Person who's rapidly gaining popularity

20. Product manager's plan

22. Curt

23. Dana Evans on "The Pitt," e.g.

24. Part of a place setting

26. Spice mix

29. Extra periods, for short

30. "Give this a taste!"

32. "___ Line Is It Anyway?"

34. Black, green or white beverage

35. Bout endings, for short

37. Professional in a classroom

38. "Meet Me in St. Louis" actor

41. Stretch across

43. Cry hard

44. Trailers before a movie, essentially

45. 'Piece of My Heart' singer Franklin

46. Wooly pack animal

48. Halloween costume for a black cat, maybe

51. Corn core

52. More skillful

54. Make thirsty

56. "We are ___ / I've got all my sisters with me"

58. Entryway that might have a microchip sensor

60. Beauty vloggers' shadow-reducing gear

62. Really serious

63. The ___ (parents, to a '00s teen)

64. This! Is! Jeopardy!

65. Forearm bone.

67. And so on

68. "Hey, you!"

All Answers

Down

1. Caterer's fuel

2. Go to a restaurant

3. Ofrendas, e.g.

4. Lots and lots

5. Taj Mahal city

6. Like a runny candle or nose

7. Prefix for "fit" or "fortune"

8. Copycat

9. Basic belief

10. Swear

11. Thing destroyed in a 1979 Atari arcade classic

12. Carbonara veggie

13. Screw up

19. Got bigger

21. ___ out (allocated)

25. Pleasant and amiable

27. Currency in CA

28. Spelling contest

31. Fish with flattened bodies

33. ___ Gruber ("Die Hard" antagonist)

34. Poke bowl protein

36. Shut with a bang

38. Phish and Goose, e.g.

39. "Well, color me surprised!"

40. Change with the times

41. "Be there in a ___!"

42. Side view of a face

47. Region around the North Pole

48. Cooks under direct heat

49. Nuts from oaks

50. Triple ___ (multitalented person)

52. Be pained

53. Radar dot

55. Make sense

57. Dosing amts.

59. Language common in the U.S. Deaf community

60. Bar in a closet

61. Possible treatment for symptoms of menopause, for short

All Answers