Class of medication whose second "S" stands for serotonin Crossword Clue

We have the 4-letter answer for Class of medication whose second "S" stands for serotonin crossword clue, last seen in the USA Today Crossword August 23, 2025 puzzle. Let us help you solve the crossword clue that has you stumped so you can finish the puzzle.

Class of medication whose second "S" stands for serotonin Crossword Answer

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Helpful Hints

(noun)
1. an antidepressant drug that acts by blocking the reuptake of serotonin so that more serotonin is available to act on receptors in the brain

Hint 2: Clue Definitions

MEDICATION (noun)
1. (medicine) something that treats or prevents or alleviates the symptoms of disease
2. the act of treating with medicines or remedies
SECOND (noun)
1. an indefinitely short time
2. a 60th part of a minute of arc
SECOND (verb)
1. give support or one’s approval to
2. transfer an employee to a different, temporary assignment
SECOND (adjective)
1. coming next after the first in position in space or time or degree or magnitude
2. a part or voice or instrument or orchestra section lower in pitch than or subordinate to the first
SECOND (adverb)
1. in the second place

Hint 3: Anagram

Unscramble the letters below to solve for today's answer.
SIRS

More USA Today Crossword (8/23/2025) Answers

Across

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16. Oil grp.

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18. Spanish for 'Miss' (Abbr.)

20. Extend, like a subscription

22. Sandwich often served with tzatziki

24. Faucet annoyance

26. Doc who might treat tinnitus

27. ___ mattress

29. Abate

31. Home to many Sherpa people

33. Strongly desired

34. Celebratory "RENT" song with the lyric "To Sontag / To Sondheim / To anything taboo"

36. Overjoys

38. Stand out on stage

39. Sprayed a hose on

41. Provided a meal for

42. Do the ___ (soda slogan)

45. "Never have I ___" (party game)

46. Apple assistant originally voiced by Susan Bennett

48. Emerge

50. Secondary social media accounts

52. Civil rights activist Horne

54. Toothed whale that's a cosmopolitan species

55. Ms. Rachel postings, e.g.

58. Stale, in a way

59. Frozen spike that tinsel resembles

60. "I ___ so high school every time I look at you"

61. Tooth-related

All Answers

Down

1. Start taking customers again

2. Dire

3. Jouster's spear

4. Prefix for "dural" or "graph"

5. "The Studio" co-creator Rogan

6. Shrewd

7. Spreads messily

8. Poke fun at

9. Egyptian fertility goddess

10. Board game calculation

12. "That's absolutely my feeling, too"

14. "That's absolutely my feeling, too"

15. Try really hard

19. Assistant

21. Certain approval form

23. Boo-boo

25. ___ XING

28. Birds similar to herons

30. "Running Point" actress Song

31. Morsel in some hot dishes

32. Dinner and a Movie channel

34. Nowadays

35. 'If you insist'

36. She sheep

37. Rolling rock?

40. Make weaker

42. Unlike someone who beats around the bush

43. "Oh, Mary!" writer and star Cole

44. Ferret or stoat

47. Revolting person?

49. Beauty entrepreneur Linda

51. Ride the tube?

53. Enthusiastic

56. Cause of extra innings

57. "Rocks"

All Answers