"Despite my best efforts . . ." Crossword Clue

We have the 9-letter answer for "Despite my best efforts . . ." crossword clue, last seen in the USA Today Crossword January 30, 2026 puzzle. Let us help you solve the crossword clue that has you stumped so you can finish the puzzle.

"Despite my best efforts . . ." Crossword Answer

↓3.

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Hint 1: Clue Definitions

DESPITE (noun)
1. lack of respect accompanied by a feeling of intense dislike
2. contemptuous disregard
BEST (noun)
1. Canadian physiologist (born in the United States) who assisted F. G. Banting in research leading to the discovery of insulin (1899-1978)
2. the person who is most outstanding or excellent; someone who tops all others
BEST (adjective)
1. (comparative and superlative of `well’) wiser or more advantageous and hence advisable
2. (superlative of `good’) having the most positive qualities
BEST (adverb)
1. from a position of superiority or authority
BEST (verb)
1. get the better of

More USA Today Crossword (1/30/2026) Answers

Across

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42. "u might wanna know . . ."

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All Answers

Down

1. Parts of your core

2. Pet that meows

4. Of worse quality

5. Intended

6. Some fourth-down plays

7. Barking sound

8. Mortgage, e.g.

9. "I want to be her" feeling

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12. Remove an identifier from

13. Smells horrible

19. Prefix meaning "eight"

21. NWSL official, for short

24. Egyptian snake

25. Show contempt

27. In the past

29. Spots with shots

30. “Oh noes!”

31. Small terrarium resident

34. "Apollo 13" org

35. Mail out

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40. Waakye grain

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All Answers