*Highly effective pain relievers Crossword Clue

We have the 11-letter answer for *Highly effective pain relievers crossword clue, last seen in the LA Times Crossword March 20, 2026 puzzle. Sometimes we all need some help finding the answer!

*Highly effective pain relievers Crossword Answer

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Helpful Hints

Hint 1: Clue Definitions

HIGHLY (adverb)
1. to a high degree or extent; favorably or with much respect
EFFECTIVE (adjective)
1. exerting force or influence
2. producing or capable of producing an intended result or having a striking effect

More LA Times Crossword (3/20/2026) Answers

Across

1. Sack

4. Dominated, in gaming

9. Living ___

14. Copier tray abbr.

15. "Do you think I was born yesterday?"

17. Ale hue

18. Forever stamp letters

19. *One who's overly concerned with pain control

21. Cheesemaking need

23. Jerry Rice, notably

24. *Gain ground, to a general

27. Citation abbr.

31. "That's strange ..."

32. Bright courtyards

33. Sounds of hesitation

36. Unwelcoming

37. Help in making things go smoothly for furniture movers

39. *Capital gain recordkeeper

43. Grungy clothing?

44. Country musics __ Brown Band

45. Altar affirmation

46. Skip over

47. Unfair accusation

50. Disavow

56. Sphinx location

58. Australian currency

59. Fitness mantra, and a hint to making the starred clues match their answers

64. 24/7 hosp. areas

65. "May I speak with you privately?"

66. ___ pants

67. Coca-Cola HQ

68. Long-necked birds

69. Charley horse, e.g.

70. Biblical possessive

All Answers

Down

1. Message on a jacket

2. Clueless

3. '50s president

4. Big citrus

5. Riesling, for one

6. Foreign policy gp.

7. Port. locale

8. Spoke in a monotone

9. Alley division

10. Italian macaroons made with almonds

11. SCOTUS justice who said, "Real change, enduring change, happens one step at a time"

12. Grand opening?

13. Make a typo, say:

16. Russian pianist Gilels

20. "Yes, __ ... ": improv principle

22. Extreme degree

25. __ Point

26. Pastoral poem

28. Roman district with a famous fountain

29. Broadcast

30. Wonder Woman weapon

32. Firepit residue

33. Needing nourishment

34. "The Little Mermaid" star Bailey

35. Tough spot

37. Charley horse, e.g.

38. Certifies

40. Brickyard racers, casually

41. United

42. Blue, in Peru

47. Flourishes

48. Banksy, for one

49. Bud

51. Container

52. Self-serve servers

53. Spiked shoe

54. "Pale Blue Dot" subject

55. 4 real?!?

57. Hill staffer?

59. Hound

60. Have debts

61. "The Cask of Amontillado" writer

62. Lacuna

63. Legendary coach Parseghian

All Answers