Main artery Crossword Clue

We have the 5-letter answer for Main artery crossword clue, last seen in the Boston Globe Mini Crossword October 13, 2026 puzzle. Sometimes we all need some help finding the answer!

Main artery Crossword Answer

→15.

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Helpful Hints

(noun)
1. the large trunk artery that carries blood from the left ventricle of the heart to branch arteries

Hint 2: Clue Definitions

ARTERY (noun)
1. a blood vessel that carries blood from the heart to the body
2. a major thoroughfare that bears important traffic
MAIN (adjective)
1. (of a clause) capable of standing syntactically alone as a complete sentence
2. most important element
MAIN (noun)
1. any very large body of (salt) water
2. a principal pipe in a system that distributes water or gas or electricity or that collects sewage

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