Mono- Crossword Clue - Try Hard Guides

We have the 3-letter answer for Mono- crossword clue, last seen in the NYT Crossword October 21, 2026 puzzle. Sometimes we all need some help finding the answer!

Mono- Crossword Answer

↓5.

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SINGLEORIGIN

(12 letters)

Helpful Hints

Hint 1: Clue Definition

MONO (adjective)
1. designating sound transmission or recording or reproduction over a single channel
MONO (noun)
1. an acute disease characterized by fever and swollen lymph nodes and an abnormal increase of mononuclear leucocytes or monocytes in the bloodstream; not highly contagious; some believe it can be transmitted by kissing

Hint 2: Other Answers Used in the Past

SINGLEORIGIN
(12 letters)

More NYT Crossword (10/21/2026) Answers

Across

1. Teacher's pet, say, in slang

7. Cumming who won a Tony for "Cabaret"

11. White lie

14. Not well known

15. Driving range?

16. N.H.L.'s Mammoth, on scoreboards

17. Driver's Ed: B

19. Alt tab?

20. Sporty vehicles, in brief

21. Reunion attendee, for short

22. Blunts

24. Crop whose trade contributed to the Opium Wars

25. Parisian permission

26. Tender bend-er

28. Gym: B+

31. ___ faire (festival with jousting)

32. Life phase, informally

33. In the thick of

34. Had dinner at home

37. Great sorrow

38. Nutrition sources

39. ___ saltado (Peruvian stir-fry dish)

40. Tavern

41. Baby boy

42. Wood shop: A

46. Have the same opinion about

47. Chemical suffix that indicates a double bond

48. "A Nightmare on ___ Street"

51. Scene that may begin "Follow that car!"

52. Like a tennis player who didn't even swing, maybe

54. Sneaker brand

55. Province with Niagara Falls: Abbr.

56. History: A+

59. Look back on with regret

60. At any point

61. Stephen King's telekinetic teen of horror

62. Figures in some rumored landings, for short

63. Short Instagram posting

64. Difficult, as a problem

All Answers

Down

1. Wrecked

2. Like a passionate solver discovering a filled-in airline magazine crossword, say

3. Edvard Munch painting, with "The"

4. Fifth Avenue retailer

6. Bird that gives pebbles as a courtship gesture

7. Bravo preceder

8. Made public

9. Actress Dowd of "The Handmaid's Tale"

10. "Can I help?"

11. First and last, say

12. "That checks out"

13. Rotten apples

18. Sly look, say

23. Kyiv's country

25. Bake-off need

27. Sch. that's home to Thomas Jefferson's Academical Village

29. Birds with a Baltimore species

30. Physicist Ohm

34. White tuna

35. One that's hard to crack

36. Airline headquartered in Dubai

37. "Are you ready for this?"

38. Fabulous, in slang

40. Info that might include "Originally from ..."

41. Open-air part of a cruise ship

43. More profound

44. Soak slowly

45. Backslide

49. Allowed

50. Fellow crew member

53. Shortcut key

54. Musical lead-in to beat

57. Blvd. crosser

58. Tried for office

All Answers

Mono- Crossword Clue Q&A

Why is UNI the answer to Mono- crossword clue?
- The prefix uni- means "one," just as the Greek-derived mono- does. Compare unicycle and monocycle.
When was Mono- crossword clue used most recently?
- This clue was last seen in the October 21, 2026's NYT Crossword.
What was the most recent answer for Mono- crossword clue?
- The most recent answer for the clue is UNI
What is the 3-letter answer for Mono- crossword clue?
- UNI
When has Mono- crossword clue been used historically?

That should be all the information you need to solve for the Mono- crossword clue! Be sure to check more clues on our Crossword Answers.

Mono- NYT Crossword Clue

Mono- Crossword Answer

Helpful Hints

More NYT Crossword (10/21/2026) Answers

Across

Down

Mono- Crossword Clue Q&A

Christine Mielke

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