Substance known as good cholesterol, briefly Crossword Clue

We have the 3-letter answer for Substance known as good cholesterol, briefly crossword clue, last seen in the New Yorker Crossword February 24, 2026 puzzle. Let us help you solve the crossword clue that has you stumped so you can finish the puzzle.

Substance known as good cholesterol, briefly Crossword Answer

↓41.

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Helpful Hints

(noun)
1. a lipoprotein that transports cholesterol in the blood; composed of a high proportion of protein and relatively little cholesterol; high levels are thought to be associated with decreased risk of coronary heart disease and atherosclerosis

Hint 2: Clue Definitions

SUBSTANCE (noun)
1. the property of holding together and retaining its shape
2. considerable capital (wealth or income)
CHOLESTEROL (noun)
1. an animal sterol that is normally synthesized by the liver; the most abundant steroid in animal tissues

More New Yorker Crossword (2/24/2026) Answers

Across

1. Likely scholarship-drive target

5. Millennial-coded reaction images

9. — -mo

12. Neither awful nor awesome

13. “Jack ___ could eat no fat” (start of a nursery rhyme)

15. ___ Zor-el (Milly Alcock’s role in the 2025 movie “Superman”)

16. Band behind a series of “High Voltage Dive Bar” pop-ups

17. Large chicken discards

19. Leader associated with the Long March and the Great Leap Forward

20. Bag for a Safeway shopper, say

21. Line from a toaster

23. Like edelweiss

24. “___ Movie” (2007 film whose main character becomes a “pollen jock”)

25. Sudoku, for one

28. “ur kidding me, right?”

32. Preposition in "The Star-Spangled Banner"

33. Fixes in a way

35. Body part that orecchiette is named after

36. Orecchiette, e.g.

39. Service aces?

42. Ability tested by Zener cards, for short

44. Smirnoff rival

45. Mistaken belief that faulty reasoning always results in an incorrect conclusion

50. Old-timey lights

51. Natural 'do

52. Actor nominated for an Oscar for playing Oskar Schindler

53. Tuck away

54. “The Accidental Tourist” author Tyler

55. Food that’s just heavenly?

56. Mortgage adjustment for short

57. N.Y. agency that unveiled a new map in April, 2025

58. Insect that visited a podiatrist’s office “ ’cause the light was on,” in a Norm Macdonald joke

59. Commedia dell'__

All Answers

Down

1. Same here

2. Neighborhood

3. Green for the red, white, and blue?

4. Soft leather slip-on, casually

5. Parts of some burlesque outfits

6. FaceTime, for example

7. The ___ Collection (art museum on the Upper East Side)

8. Bob who was the original host of “America’s Funniest Home Videos”

9. Yemen’s capital

10. Build, as a monument

11. Container for amontillado in an Edgar Allan Poe title

14. Palpitate

15. Conforming with Jewish dietary law

18. 00110110 and 00110111, e.g.

20. “I know something you don’t” expression

22. Print-quality fig.

25. Song on a “faves” playlist, maybe

26. Scratch or dent

27. Command that people look forward to?

29. Endeavor to find

30. Heroine of a video-game series with more than a hundred million units sold

31. Twelve-mo. spans: Abbr.

34. River that forms much of the Georgia-South Carolina border

37. “I want to know!”

38. C. S. Lewis character who symbolizes Jesus

40. Frames of Roger Rabbit, perhaps

43. Fictional nation home to Katniss Everdeen

45. Barely audible

46. Pigeon pose, for one

47. Third-stringers

48. ___ question (something asked when solving a lateral-thinking puzzle)

49. "That hurts!"

50. Partner of glitz

53. Spanish Mrs.

All Answers