___ best friend Crossword Clue

We have the 4-letter answer for ___ best friend crossword clue, last seen in the NYT Crossword October 22, 2025 puzzle. This answer will help you finish the puzzle you’re working on.

___ best friend Crossword Answer

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Hint 1: Clue Definitions

FRIEND (noun)
1. a member of the Religious Society of Friends founded by George Fox (the Friends have never called themselves Quakers)
2. a person who backs a politician or a team etc.
BEST (noun)
1. Canadian physiologist (born in the United States) who assisted F. G. Banting in research leading to the discovery of insulin (1899-1978)
2. the person who is most outstanding or excellent; someone who tops all others
BEST (adjective)
1. (comparative and superlative of `well’) wiser or more advantageous and hence advisable
2. (superlative of `good’) having the most positive qualities
BEST (adverb)
1. from a position of superiority or authority
BEST (verb)
1. get the better of

More NYT Crossword (10/22/2025) Answers

Across

1. Spots for cozy dates

6. Slope

10. What A's and B's are good for

13. Person with terrible manners

14. Broadway great Menzel

16. Nickname that's an alternative to Cam

17. Some basic guidelines [2, Spanish]

19. Nonprofit's domain name ender

20. Paris agreement

21. Take to court

22. Act smart

24. Molecule with a non-unique formula

26. Fluorescent gemstone [4, Danish and Norwegian]

27. "Girls" creator Dunham

28. Slightly

30. Some parallel bars

31. Agrees (with)

33. Rarely visited places on earth

34. Climactic baseball event … or what the starts of 17-, 26-, 44- and 52-Across form?

36. "Breaking Bad" sister-in-law

37. Touches and Shuffles

38. Black prom rentals

39. Bubbly bar

40. Idiomatic sticking point

44. Chemist who co-discovered 26-Down [8, Italian]

46. It's controlled in meditation

48. Food spread popular in England

49. Levi's competitor

50. Toilet paper thickness

51. ___ out of house and home

52. Carpe diem [16, French]

55. Picasso's "___ Demoiselles d'Avignon"

56. A little under half of humanity

57. Entertain

58. Establishes what is, informally

60. Sidekick of Dora the Explorer

All Answers

Down

1. Natural remedy that's used to treat anxiety

2. Make hot and bothered

3. Kind of cuisine

4. Traveler's info, informally

5. Electroreception, for sharks

6. Jaunt on a hay wagon, e.g.

7. Me?!

8. "You got that right!"

9. Key to search with, maybe

10. Fans of a band

11. Whirling visual effects in video games

12. Watchful guardians

15. Part of a belt

18. Built to last

23. Gel

25. David Bowie's astronaut persona

26. Atomic reaction co-discovered by 44-Across

29. Word with flower or feather

32. Expression such as "Top o' the mornin'"

33. Certain sports wager

34. Sara Bareilles musical set in a diner

35. Clean water org.

36. Shape-shifted

38. Language on the Horn of Africa

39. Young woman, in Australia

41. Outkast or Eric B. & Rakim

42. "Thank god!"

43. "You're quite right"

45. Premier squad

47. Recovery phase

49. Not as much

53. In a chill state

54. Subculture associated with skinny jeans

All Answers