Drug such as Lexapro or Prozac: Abbr. Crossword Clue

We have the 4-letter answer for Drug such as Lexapro or Prozac: Abbr. crossword clue, last seen in the New Yorker Crossword August 25, 2026 puzzle. Let us help you solve the crossword clue that has you stumped so you can finish the puzzle.

Drug such as Lexapro or Prozac: Abbr. Crossword Answer

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Helpful Hints

(noun)
1. an antidepressant drug that acts by blocking the reuptake of serotonin so that more serotonin is available to act on receptors in the brain

Hint 2: Clue Definitions

PROZAC (noun)
1. a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade names Prozac or Sarafem); it is thought to work by increasing the activity of serotonin in the brain
DRUG (verb)
1. use recreational drugs
2. administer a drug to
DRUG (noun)
1. a substance that is used as a medicine or narcotic

Hint 3: Anagram

Unscramble the letters below to solve for today's answer.
SIRS

More New Yorker Crossword (8/25/2026) Answers

Across

1. Using technology to try to extend one’s life span, say

15. Author of “So Big” and “Giant”

16. Confirmed couple

17. Figure that’s typically high for a hybrid vehicle

18. Zippo

19. “I’m right here, by the way”

20. Blab pointlessly

22. Word that rhymes with, and can precede, “pal”

23. “Oranges Are ___ the Only Fruit” (1985 coming-of-age novel)

24. Nickelodeon’s “Kenan & ___”

26. Hybrid citrus

28. Acquire on a torrent site, maybe

30. Subway ___ (MetroCard predecessor)

31. Part of a dress

32. Far from sunny

33. Spot check at the psychologist’s office?

37. Go on git!

38. Fabric named for its city of origin, which is now called Chennai

39. Malarkey

41. Underwent a change in plumage

42. Most likely …

44. "All About ___" (1950 film)

45. N.C.A.A. group that includes the Stanford Cardinal

48. Part of a merch-table pile

49. Wrap that might protect a wrap

51. Florida panther, e.g.

52. H.S. exam with “8/9” and “10” versions

54. Eatery that requires a significant seed investment?

57. Is under the weather

58. Power once ruled by Atahualpa

59. Do a Don Corleone impression, say

60. Big sale

All Answers

Down

1. Started

2. State whose official vegetable is the potato

3. Start

4. Winner of the first two FIFA Women’s World Player of the Year awards

5. Org. whose top-movie lists include “100 Years . . . 100 Laughs” and “100 Years . . . 100 Passions”

6. Collectible for an animation fan

7. Dumplings sometimes served on Purim

8. Letter-shaped beam

9. Cancel out

10. “Past Lives” star Lee

11. Envy or pride, for example

12. Romantic gesture for a couple making a scene?

13. Urgent warning

14. “No one else is around”

21. Doc who might treat vertigo

24. Joshes

25. Adams who has called New York City “the Seoul of America,” “the Istanbul of America,” and “the Kyiv of America”

27. Stop functioning

28. Like pumice stones

29. Statement on Día de San Valentín

31. Possible rewards for novel ideas?

33. Colonial predecessor of Zimbabwe

34. Record of the year

35. Media-room purchase

36. Support for either side of a hammock

37. Performed as expected, in a way

40. “¡No ___!” (“I give up!”)

41. Breed of sheep known for its ultrafine wool

43. Like zealous fans

45. Review

46. Short summons

47. Babysitter or nurse, e.g.

50. “Play with the bow” instruction

51. Livens (up)

53. Recipe amt.

55. Mo. for Philippine-American War Memorial Day

56. Cassowary relative

All Answers