"Lose the ___, dude!" Crossword Clue

We have the 4-letter answer for "Lose the ___, dude!" crossword clue, last seen in the NYT Crossword September 15, 2026 puzzle. This answer will help you finish the puzzle you’re working on.

"Lose the ___, dude!" Crossword Answer

↓46.

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Helpful Hints

Hint 1: Clue Definitions

LOSE (verb)
1. fail to perceive or to catch with the senses or the mind
2. be set at a disadvantage
DUDE (noun)
1. a man who is much concerned with his dress and appearance
2. an informal form of address for a man

Hint 2: Anagram

Unscramble the letters below to solve for today's answer.
DUET

More NYT Crossword (9/15/2026) Answers

Across

1. Laffy ___, candy with a rhyming name

6. Poker buy-in

10. "The windows to the soul," metaphorically

14. Frighten

15. Villains hideout

16. American Girl toy

17. Cringey ad campaign going viral, for example

19. Madonna's "La __ Bonita"

20. Goes out with

21. Piglet and Pooh's marsupial friend

22. "Well, in that case ..."

24. Clic Stic and Wite-Out brand

26. Character at the heart of the "Who shot ...?" cliffhanger of 1980s TV

27. Colombian cornmeal cake

29. San Jose, ___ Rica

30. Oculus Rift or Meta Quest 3

32. Opposite of chaos

36. Texter's "I think"

37. Started a game of blackjack, say

38. 18-wheeler

39. Agrees nonverbally

41. Red root vegetables

44. Kind of rally at high school

45. Put up as a building

47. Many characters on “The Pitt”

49. Quick

51. Group holding a nominating convention

52. Scannable squares often used in place of paper menus

55. ___-Wan Kenobi

56. Rang, as a bell

57. Pooch's bark

59. Paddington Bear's country of origin

63. What a light bulb represents, in comics

64. Puppet dragon of 1960s kids' TV

67. Bottom-heavy fruit

68. Britney Spears's "___! ... I Did It Again"

69. Perform better than

70. Daughter's brothers

71. Exam

72. French fries-to-be

All Answers

Down

1. Cough syrup amts.

2. Farmland measure

3. Haircut that transitions from shorter sides to longer top

4. Ultimate ___ (team sport)

5. Word of consent

6. Too

7. Grp. with a phonetic alphabet

8. Cause for overtime

9. Screw-ups

10. Conflicts over Wikipedia content

11. Mario's dinosaur sidekick

12. Actress Pompeo of "Grey's Anatomy"

13. Vernacular found in Urban Dictionary

18. Place for coin-op game machines

23. Kind of high-fat diet

25. Tablet with Pro, Air and mini versions

26. Scribbled down

27. Knight's wear

28. The "R" in R.I.

29. The "log" in "ants on a log"

30. Trellis-climbing plant

31. "Light" Jedi weapons

33. Railroad station

34. Manicurist's filing board

35. Laces (into)

40. Well-educated sorts

42. Fill back to capacity, as a glass

43. Healing cover

48. Causes to make a mistake

50. Bit of fiery cinnamon candy

52. Cotton swabs not recommended for ear canal use

53. Cowboy contest

54. Fresh from the dishwasher

57. Grindr and Tinder, for two

58. Sign of decay

60. ___, Brute?

61. "Ant-Man" star Paul

62. Sights that make you go "What the …?!"

65. ___ v. Wade (1973 Supreme Court decision)

66. Rejections

All Answers